Welcome to the SPARC Portal — Advancing bioelectronic medicine through open science

Our vision: Integration of Data, Knowledge, Computational Modeling, and Spatial Mapping for the peripheral nervous system will greatly advance scientific understanding and will deliver significant impacts for clinical medicine.

What Can I Do With SPARC?
Browse, View, and Get Data and Models
Freely use curated experimental data, protocols, and models of the autonomic nervous system.
View 2D and 3D Anatomical Maps
Discover relationships and datasets with interactive connectivity maps featuring different species.
Create Computational Pipelines
Connect to the o²S²PARC platform to build and explore modeling and data analysis pipelines.
Include SPARC in your proposals
2023 NIH Data Sharing Policy is in effect now. Requirements are met when your grant includes SPARC.

Projects & Datasets
Here is a project you might be interested in:
Comprehensive structural and functional mapping of mammalian colonic nervous system
Colonic disorders are multifaceted and range from functional chronic constipation, diarrhea, diverticulitis, irritable bowel syndrome (IBS), inflammatory bowel diseases (IBD), Clostridium difficile colitis, cancer, Parkinson, to physical trauma such as spinal cord injury. These conditions greatly impact the quality of life of patients and their high prevalence and morbidity costs an estimated $21 billion annually. The proposed multidisciplinary approaches and detailed anatomical and functional mapping of the innervation of the colon will provide critical knowledge in a large animal model and in humans, which is essential for the development of new therapeutic approaches including electroceutic modalities to efficiently treat colonic diseases.
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Featured Datasets
In vivo mapping of gastric electrical activation with manganese enhanced magnetic resonance imaging
We used MRI to map gastric electrical activation following meal consumption. Manganese ions were used as a surrogate of calcium ions to map the increase of calcium influx, presumably into smooth muscle cells.
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Open Office Hours
Join one of our weekly office hours to ask questions and learn more from the SPARC Data Resource Center Team.