Welcome to the SPARC Portal — Advancing bioelectronic medicine through open science!
Our vision: Integration of Data, Knowledge, Computational Modeling, and Spatial Mapping for the peripheral nervous system will greatly advance scientific understanding and will deliver significant impacts for clinical medicine.
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Projects and Datasets
Here is a project you might be interested in:
Optical nanosensors detect neurotransmitter release in the peripheral nervous system
We will image volumetric release of acetylcholine in the peripheral nervous system and spleen, with a combination of nanoscale tools and a genetically engineered axolotl. Ultimately, we will use this toolset for chemical mapping of brain-immune system signaling, specifically in the vagus nerve and spleen. In addition, other fields involving neurotransmitter signaling in the peripheral nervous system could be benefited, including limb regeneration and prosthetic interface.
Here is a dataset you might be interested in:
Identification of peripheral neural circuits that regulate heart rate using optogenetic and viral vector strategies
Data from the innervation of intact mice hearts and the mapping of parasympathetic and sympathetic neural circuits which control heart rate. This data set identifies the cholinergic and noradrenergic neurons which project to the sinoatrial node.
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